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2.22 Data and statistical analysis The data and statistical analysis comply with the recommendations on experimental design and analysis in pharmacology (Curtis et al., 2018)

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With obesity, diabetes, cardiovascular disease, liver disease, and possibly neurodegenerative disease all becoming viable markets, the total addressable market is likely to reach or exceed USD 100-150 billion globally (perhaps more depending on healthcare policy)

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Importantly, with the advent of more potent GLP-1 receptor agonists like semaglutide, it is crucial to study these newer medications individually rather than grouping them with older drugs in the same class, as their effects may differ significantly, she added