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However, in recent years, dedifferentiation, senescence and other forms of cell death, such as autophagy, pyroptosis and ferroptosis, have been found to be involved in the loss of cells

This study illustrates the importance of inhibiting the glutathione metabolic pathway regulated by Nrf2 for tumor therapy, and at the same time provides a new idea for the treatment of malignant tumors with IDH1 mutations

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Results showed improvement in GI motility endpoints with an acceptable safety profile

This helps assess whether early growth is on track