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The possible cardioprotective mechanisms of GLP-1 RAs include reducing epicardial fat tissue thickness, preventing activation of the reninangiotensinaldosterone system, improving myocardial energy metabolism, reducing systemic inflammation and cardiac oxidative stress, and delaying the progression of atherosclerosis
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December, 2025 The U.S
These inflammatory cytokines not only amplify the inflammatory response but also facilitate the activation and recruitment of immune cells, such as DCs and NK cells, which play a pivotal role in the pathogenesis of vitiligo (65)
The discrepancy might suggest that the ETC dysfunction is secondary to other mechanisms that closely regulate mitochondria
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