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10.1016/j.bbi.2021.01.003 5 DrgeH.NeumannT.BehrendsM.SkyschallyA.SchulzR.KasperC.et al (2000)

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Severe nausea on GLP-1 medications combined with illness-related vomiting creates a dangerous situation where: Dehydration can develop rapidly You cannot absorb oral medications or nutrients The GLP-1 medication may worsen gastrointestinal symptoms Risk of electrolyte imbalances increases When to seek emergency care : If you cannot keep any fluids down for 12+ hours, notice dark urine, feel dizzy upon standing, or have a rapid heartbeat, seek medical attention immediately

This is among the first long-acting amylin-based medications to reach late-stage clinical trials for weight management

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