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When to Seek Medical Advice About Swelling or Fluid Retention While water retention is not a typical side effect of GLP-1 receptor agonists, any new or worsening swelling warrants medical evaluation to identify the underlying cause and ensure patient safety

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Incorporating these medications into a long-term wellness plan involves constant evaluation

N., Deanfield J., Pratley R., et al., Semaglutide Versus Placebo in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction: A Pooled Analysis of the SELECT, FLOW, STEPHFpEF, and STEPHFpEF DM Randomised Trials, Lancet 404, no

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