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Depending on the dose, a fraction of APAP is converted into a highly reactive toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), by several P450 cytochromes [34]

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As animals were obtained in six separate batches due to operational limitations and grouped in cages, the survival curves were plotted using the KaplanMeier method

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TET family proteins, especially TET2, are downregulated during EBV infection, and TET2 may function as a resistance factor against EBV-induced DNA methylation acquisition