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Subsequently, the cells were treated with PBS, Ru(II)-OH, NP2, or NP4 at various final concentrations ranging from 0.025 M to 15 M for 48 h

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Immune functions As among the most abundant intracellular proteins, HSP70s serve as signals of compromised cell integrity, namely, damage-associated molecular patterns (DAMPs), when released extracellularly (Kaneko et al., 1997)