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Mitochondrial dysfunction prevents repolarization of inflammatory macrophages

Kendall went on to be awarded the Nobel Prize in Physiology or Medicine for his work on corticosteroids in 1950

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Clinical testing of IGF-IR-targeted agents The identification of IGF-IR as an important cancer-promoting protein has stimulated the development of many IGF-IR-targeted agents, including anti-IGF-IR mAbs and small-molecule inhibitors

The following reaction conditions were used: an initial cycle at 94C for 3 min, 30 cycles of 94C for 5 s and 60C for 20 s and a final melting curve from 73C to 93C to ensure that only one product was amplified