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The colon has the largest microbial load in the body and contains about 10 14 bacteria with the dominant phyles of Firmicutes (renamed Bacillota), Bacteroidetes (Bacteroidota), Actinobacteria (Actinomycetota), and Proteobacteria (Pseudomonadota) ( Enterococcus , Lactobacillus , Ruminicoccus , Bacillus , and Clostridium , representing 95% of the Firmicutes phylum

Additionally, it influences the upregulation of growth hormone receptors, which plays a pivotal role in tissue healing and regeneration

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This suggests the peptide may support cellular energy production while reducing oxidative stress

Along with lactate, the level of TCA cycle activity is known to be reduced/bypassed under inflammation stress