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Because semaglutide directly affects gut movement and the release of digestive enzymes, it can easily disrupt the natural rhythm of digestionespecially during the first few weeks of treatment

In theory, targeting two different metabolic pathways could provide a synergistic effect

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Its key roles include triggering the release of insulin, blocking blood sugar spikes, slowing stomach emptying, and increasing fullness after eating

Common Side Effects The most commonly reported adverse events are gastrointestinal in nature: Nausea (approximately 20-44% of participants) Diarrhea (approximately 30%) Vomiting (approximately 24%) These symptoms are typically mild to moderate in severity, tend to occur most frequently during dose escalation, and generally diminish over time as tolerance develops