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Another study demonstrated a significant increase in heart weight in female, but not male, Sprague-Dawley rats with 13 weeks of daily nose-only inhalation exposure to the smoke of a custom-blended experimental cigarette smoked under FTC conditions (Coggins et al

Bmal1 downregulation compromises antioxidant defenses, potentially involving NRF2 and HO-1 (Wu et al

In cooler regions indoor heating will greatly affect the amount of moisture that is needed so winter seasons will create the largest humidity demand